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As with all studies, there are strengths and limitations associated with this work

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The observed inorganic particles may originate from the tobacco and the wrap paper as was shown in analysis of the paper and tobacco materials, possibly due to the air flow through the IQOS stick during testing, whereas the carbonaceous material is most likely originating from the glycerol additive part of the IQOS tobacco material (boiling point of glycerol is 290 C)